A road trip from San Francisco to Los Angeles is one of the most scenic drives in the world, offering breathtaking coastal views, charming small towns, and iconic landmarks. Whether you prefer a fast drive down Interstate 5 or a more scenic journey along Highway 1, there are multiple routes to choose from. Here are the three best road trip routes for an unforgettable California adventure.

1. Pacific Coast Highway (Highway 1) – The Scenic Route
If you’re looking for stunning ocean views, picturesque towns, and incredible coastal landscapes, the Pacific Coast Highway (PCH) is the ultimate road trip route. This legendary drive follows the California coastline, offering some of the most breathtaking scenery in the state.
Highlights Along the Way:
- Monterey & Carmel-by-the-Sea – Visit the famous Monterey Bay Aquarium, explore Cannery Row, and enjoy the charming art galleries and cafes in Carmel.
- Big Sur – Drive across the stunning Bixby Bridge, stop at McWay Falls, and take in the rugged coastal beauty of Pfeiffer Beach.
- San Simeon – Tour the lavish Hearst Castle, once home to newspaper tycoon William Randolph Hearst.
- Santa Barbara – Relax on the beaches, explore the Funk Zone for wine tasting, and visit the historic Santa Barbara Mission.
This route takes about 10-12 hours of driving time, but you’ll want to spread it over 2-3 days to truly enjoy all the stops along the way.

2. US Route 101 – The Wine Country & Coastal Route
For a mix of coastal beauty, rolling vineyards, and charming towns, taking US Route 101 is a fantastic choice. This route runs parallel to Highway 1 but moves inland at certain points, making it a great alternative for those who want a balance between scenic drives and quicker travel times.
Highlights Along the Way:
- Sonoma & Napa Valley – Start your journey with wine tasting in California’s famous wine country.
- Paso Robles – Another fantastic wine region known for red blends and hot springs.
- San Luis Obispo – Explore this charming town, visit Bubblegum Alley, and stop by Madonna Inn for its quirky decor.
- Malibu – Enjoy the beautiful beaches, hike in Malibu Creek State Park, or grab a bite at Malibu Farm on the Pier.
The US-101 route is faster than Highway 1 but still offers plenty of scenic views and attractions along the way.

3. Interstate 5 – The Fastest Route
If you’re short on time and just need to get from San Francisco to Los Angeles quickly, Interstate 5 (I-5) is the most direct route. This highway runs through California’s Central Valley, bypassing most coastal attractions but offering a faster drive.
Highlights Along the Way:
- Harris Ranch – A popular stop for steak lovers, known for its famous Harris Ranch Beef.
- Tejon Outlets – A great place to shop for discounts before reaching Los Angeles.
- Gorman & Pyramid Lake – A nice scenic stop before entering the LA area.
This route takes about 5-6 hours without stops, making it ideal for travelers who need to reach their destination quickly.